Advanced Organic Chemistry

Graham de Ruiter
May 4, 2022

In this course we will discuss the reactivity of organic and metal-organic molecules by analysis of the frontier molecular orbitals. We will work our way up from simple diatomic molecules unto more complex organometallic systems. We will discover the roles of molecular symmetry and importance of molecular orbitals in order to understand the reactivity. The following topics will be discussed during the course

Molecular Symmetry
Molecular Orbital Diagrams of diatomic and triatomic molecules
Molecular Orbitals Diagrams of Hydrocarbons
Binding of Organic Molecules to Metal Complexes
Orbital Mixing and Reactivity in Organic Reactions

The course will be held on:

Monday: 11:30-12:30

Tuesday: 14:30-16:30

Course Content

Introduction

1.01 | Introduction

Molecular Orbitals of Diatomic and Triatomic Molecules

2.01 | Diatomic Orbitals and the Method of Inspection

2.02 | Molecular Orbitals and the Character Table

2.03 | Molecular Orbitals of Ammonia & Principles of Sigma and Pi

2.04 | Molecular Orbitals of Complex Molecules; SF6

2.05 | Acid/Base Chemistry

Electron Deficient Bonding: Three Center Two Electron Bonds

3.01 | The MO Diagram of Diborane Part 1

3.02 | The MO Diagram of Diborane Part 2

Orbital Mixing

4.01 | Orbital Mixing in s,p, and d-Orbitals

Molecular Orbitals of Complex Organic Molecules: Hydrocarbons & Olefins

5.01 | The MO-Diagram of Ethylene and Butadiene

5.02 | The MO-Diagram of Cyclopentadienide

Interaction of Organic Molecules with Metals

6.01 | The Octahedral Ligand Field and Molecular Orientation Part 1

6.02 | The Octahedral Ligand Field and Molecular Orientation Part 2

Homework Exercise

7.01 | Homework Exercise and Answer Key